Synthesis and Biological Activity of N-acyl Anabasine and Cytisine Derivatives with Adamantane, Pyridine and 1,2-Azole Fragments
A series of N-acyl derivatives of anabasine and cytisine were prepared, to discover novel, natural product-based medicinal agents.All synthesized compounds were tested for antimicrobial, antifungal, antiviral and analgesic activity.The most pronounced antibacterial activity was shown by the compounds with isoxazole fragments, while the Pulse Sensor